Special Issues

Membrane Interactions of Cell-Targeted Drugs and Nanoparticles
Editor: Mohammad Ashrafuzzaman

Submission Deadline: 30 June 2024 (Status: Open)


Special Issue Editor(s)


Mohammad Ashrafuzzaman      Email   |   Website
1. Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia
2. MDT Canada Inc., Edmonton, Alberta, Canada

Interests: membrane; cell; disease; drug; protein; nanoparticle; aptamer; biophysics


Special Issue Information

Dear Colleagues,

Cellular membranes, such as plasma membrane, mitochondrial membrane, and nuclear membrane, act as barriers and transporters of theranostic (therapeutic and diagnostic) agents (drugs and nanoparticles) that are primarily chosen to target cell-based structures. Many nanoparticles are also used as carriers of drugs when the nanoparticle-drug complexes are adsorbed by membranes and then delivered to cellular interior regions. In the case of cell-originated diseases, many cell-based structures experience structural alterations or mutations. In therapeutics, these altered structures are targeted to get repaired or eliminated. The physicochemical properties of both membranes and the membrane interacting agents mutually dictate to determine their permanent or temporary membrane residency potency or the membrane delivery into cellular target structures. Understanding the membrane interactions of drugs and nanoparticles is thus very important for drug discovery, drug delivery, nanoparticle design, creating drug-nanoparticle complexes and imaging cellular structures. Furthermore, the membrane interactions in drugs and nanoparticles may also cause membrane-based cytotoxicity. In this special issue, we welcome articles to address all these medically relevant topics and phenomena. Both research and review articles using biophysical, biochemical, biological, pharmaceutical, medical will be considered for publication. In addition, we welcome articles covering theoretical, experimental, and computational research data.

Mohammad Ashrafuzzaman
Guest Editor


Keywords

membrane; cell; disease; drugs; membrane proteins; lipids; nanoparticles


Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://www.biolifesas.org/journalx_brha/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.

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