Journal of Biological Regulators and Homeostatic Agents

Founded in 1987
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Print ISSN: 0393-974X
Electronic ISSN: 1724-6083

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20 October 2022, Volume 36 Issue 5

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Anxiety, Depression, Distress, and Resilience in Patients with Haematological Malignancies. The Effect of Nine Weeks of Psychological Support on Psychological Status and Stress Biological Markers

Marcello Aragona, Katia Marabello, Carmen Mannucci, Ilaria Ammendolia, Fabrizio Calapai, Angela Alibrandi, Sabina Russo, Rossana Leanza, Caterina Musolino, Alessandro Allegra

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1201-1210; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.131

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Article

The Significance of Discs Large Homolog 2 Expression in Hepatocellular Carcinoma: A Laboratory Study

Jia-Wei GU, Run-Qi HONG, Yi ZHANG, Geng-Ming NIU, Zhi-Qing HU, Xiao-Tian ZHANG, Zhi-Peng CAO, Xi LI, Chong-Wei KE

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1211-1222; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.132

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Article

Dexmedetomidine Alleviates Pulmonary Edema by Modulating Na,K-ATPase in a Rat Model of Acute Lung Injury via the α₂AR/PI3K/Akt Signaling Pathway

Yuanxu Jiang, Zhewei Huang, Jing Xu

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1223-1235; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.133

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Article

Atorvastatin Attenuates CCL20 Expression via the NF-κB Pathway in OxLDL-Induced Macrophages: A Potential Mechanism of Antiatherosclerosis

Chen Chen, Kaijing Wang, Chenglv Hong, Xiao Chen, Lu Lin, Xiangxiang Shi

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1237-1245; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.134

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Article

Novel Insights: Differentially Expressed tsRNAs Modulate the Advance of Early-Stage Diabetic Nephropathy in Mice

Heng-Mei Zhu, Na Liu, Liang Luo

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1247-1257; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.135

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Article

Exosome-Derived miR21 Elicits an Epithelial Ovarian Cancer Cell-Promoted Phenotype

Xiaoyan Xie, Mu Xu, Hangjing Gao, Xianjing Chen, Liangzhi Cai

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1259-1267; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.136

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Article

Development of a Nomogram and Use a of 7-Methylguanosine Methylation-Related miRNA Signature as a Prognostic Target in Triple-Negative Breast Cancer

Qinyan Shen, Liting Lv, Kangbin Wu

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1269-1279; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.137

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Article

Anti-Inflammatory and Biofilm Inhibition Potential of Methanolic and Aqueous Extract of Elettaria Cardamomum and Cichorium Intybus

Muhammad Shahid, Muhammad Kashif, Komal Khan, Aziz Ur Rehman, Fozia Anjum, Mazhar Abbas, Samiah H. Al-Mijalli, Shaista Abbas, Abid H. Shahzad, Muhammad Riaz, Munawar Iqbal, Mahvish Fatima

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1281-1289; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.138

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Article

c-Myc Positively Enhances RPL34 Expression to Regulate Osteosarcoma Cell Proliferation

Piwei Huang, Minghui Wei, Shufan Ji, Maolin He

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1291-1298; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.139

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Article

Deciphering the Prognostic Implications of T Cell Marker Gene Signatures in Hepatocellular Carcinoma Tumor Microenvironment

Chenyu Jiang, Jiangmin Liang, Yiwan Wang, Chaohui Wang, Shenyu Wei, Junjie Ni, Yaojian Shao

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1299-1310; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.140

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Article

Effectiveness of a Fermented Functional Food on Telomere Dynamics and miRNAs in Middle-Aged/Elderly Healthy Individuals: A 2-Year Randomized, Double-Blind, Controlled Clinical Trial

Marotta Francesco, Zerbinati Nicola, Lorenzetti Aldo, Ayala Antonio, Barbagallo Mario, Munoz Mario, Rasulova Saida, Osato Maki

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1311-1319; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.141

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Article

Prognostic Significance of Lymphocyte-to-Monocyte Ratio in Patients with Osteosarcoma: A Meta-Analysis

Junjun Cha, Shipan Li, Jidong Sui

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1321-1329; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.142

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Article

Construction of a Prognostic Predicting Model for Advanced Gastric Cancer Patients Treated with PD-1 Inhibitors in Combination with Taxane-Based Chemotherapy

Ying Yang, Dapeng Li, Meng Shen, Yan Wu, Caihua Xu, Mengyao Wu, Kai Chen

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1331-1340; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.143

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Article

The Impact of PD-L1 and Correlated Markers on the Prognosis of Adenocarcinoma NSCLC Patients

Xuyu Bian, Jiajia Wang, Wei Chen, Mengdan Xu, Caihua Xu, Mengyao Wu, Min Tao

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1341-1348; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.144

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Article

Transcriptomic Analysis of Neuropathic Pain in the Mouse Spinal Cord Following Peripheral Nerve Injury

Lili Jiang, Zhe Peng, Yuhui Deng, Peiyu Chen, Bingwei Yu, Miaosen Guo, Jinping Huang

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1349-1358; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.145

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Article

Study on the Changes of Intestinal Flora in Patients with Colorectal Cancer

Ying Zhang, Weimin Jiang, Qinglong Yang, Xiao Yu, Chen Cui, Xiangyang He

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1359-1367; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.146

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Article

Electroacupuncture Treatment Alleviated Intracolonic Capsaicin-Induced Rectal Visceral Pain by Inhibiting the Expressions of TRPV1 and P2X4R and Blocking MAPK Pathway

Yahong Xue, Fei Liu, Shaohua Huangfu, Yunlin Jiang, Xiaofeng Wang

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1369-1378; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.147

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Article

The Relation between microRNA-16 and Cardiac Remodelling Induced by Acute Myocardial Infarction: A Case Control Study

Xingmei Huang, Lei Zhang, Hongxia Li, Lianhua Han, Xiaobin Yu

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1379-1385; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.148

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Article

MicroRNA-144-3p Promotes Erastin-Induced Ferroptosis by Targeting SLC7A11 in NSCLC Cells

Zhucheng Yin, Hongli Xu, Yanli Nie, Ping Lu, Yifei Ma, Xin Liang, Lingyi Xiong, Xiangchen Zhang, Shaozhong Wei, Xinjun Liang

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1387-1396; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.149

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Article

Dexmedetomidine Ameliorates Morris Water Maze Learning in Rats with Postoperative Cognitive Dysfunction by Enhancing Mitophagy and Inhibiting the Activation of the NLRP3 Inflammasome

Congying Zhu, Lingyang Chen, Nanjin Chen, Yongqing Ye, Danjiang Lin

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1397-1407; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.150

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Article

LC-MS/MS-Based Peptide Mapping Explores the Contribution of Human Milk to Breast Milk Jaundice

Jiahua Zhang, Ziman Fu, Weiwei Jiang, Yingying Zhang, Yiting Wang, Chunjian Shan

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1409-1418; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.151

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Article

Roles of 630 nm Red Light-Emitting Diode in Inhibition of RhoA Signal Transduction Pathway via Reducing PLEKHG5 Expression and Alleviation of Inflammatory Response in Macrophages

Kaibo ZHANG, Feng LIANG, Majjid A QARIA, Haihe WANG, Monan LIN, Fengmin ZHANG

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1419-1426; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.152

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Article

Reg3b Alleviates Cisplatin-Induced Apoptosis of Hair Cells in Cochlear Organ of Corti

Xiao-Bo Mao, Bo Yue, Yu Han, Xiao-Dong Chen

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1427-1437; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.153

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Article

Caulis Spatholobi Ameliorates Pregnancy-Induced Hypertension in Mice by Regulating Hepcidin Expression and Iron Homeostasis

Zhongying Ding, Yan Lu, Haiyan Zhang, Ke Hua, Guosong Shen

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1439-1449; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.154

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Article

SSBP1: A Potential Prognostic Marker of Lung Adenocarcinoma

Jiye Liu, Can Xu, Jiahe Wang

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1451-1465; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.155

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Article

Tripterygium Glycosides Weakened Enteric Ischemia/Reperfusion Detriment via the Nrf2/HO-1 Pathway

Linxue Wang, Wei Luo

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1467-1477; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.156

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Article

MicroRNA-17-5p Enhances Radiosensitivity in Prostatic Cancer by Targeting MeCP2

Guangqing Fu, Wei Chen, Xiang Zeng, Xiaohui Luo

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1479-1487; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.157

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Article

Potential Mechanisms of Er Chen Decoction against Polycystic Ovary Syndrome Based on Network Pharmacology Strategy

Qiaorui Yang, Zhenliang Fan

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1489-1499; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.158

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Article

Hypoxia-Induced Downregulation of MiR-199a-3p Promotes Proliferation, Invasion and Epithelial-Mesenchymal Transition in Colorectal Cancer Cells

Limiao Lin, Bihong Chen, Yanqing Li

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1501-1509; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.159

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Article

Construction of an Evaluation Tool for Episiotomy and an Analysis of Its Clinical Effects

Xue-Na Wu, Zhen-Dong Fu, Ying Cao, De-Sheng Cai, Jun-Lan Xu, Qi Chen

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1511-1518; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.160

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Article

The Effect and Mechanism of Action of Danhong Injection on Lipid Peroxidation and Endothelial Dysfunction Coronary Heart Disease: An Animal Study

Zhiyuan Zhang, Zhongbao Ruan, Guixian Song, Ruzhu Wang, Chunfang Hu, Li Zhu

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1519-1526; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.161

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Article

LINC00265 Promotes IL-1β-Induced Chondrocyte Inflammation and Extracellular Matrix Degradation by Activating the MAPK/NF-κB Pathway

Hui Zhao, Peng Yan

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1527-1534; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.162

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Article

Correlation of Plasma Asymmetric Dimethylarginine Expression with Early Neurological Deterioration and Recurrence in Patients with Acute Cerebral Infarction

Yuanwei Wang, Li Du, Xian Zhang, Ying Wang, Liwu Lu, Rui Wei, Benchi Xu, Xiaojie Hu

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1535-1541; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.163

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Article

WAVE3 Promotes Glioma Cells Migration and Invasion via EMT

Yifen Shen, Ying Tang, Yongchun Gu, Chao Liu

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1543-1554; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.164

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Article

Identification of Necroptosis-Related Genes in Lung Adenocarcinomas: A Novel Prognostic Model

Pengcheng Zhang, Jie Zhou, Weiping Zhang, Kai Xu, Yongfu Zhu, Mingran Xie

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1555-1568; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.165

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Article

The Effect of PIN1 Inhibitor Juglone on the Spinal Cord after Acute Spinal Cord Injury (ASCI) and Its Mechanism of Action: An Animal Study on Rats

Rongmou Zhang, Peiwen Wang, Huafeng Zhuang, Haiming Yu, Hao Xu, Xuedong Yao

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1569-1577; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.166

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Article

The Mechanism of Renal Cell Damage after Acute Kidney Injury (AKI): A Laboratory Animal Study

Fang Chen, Taotao Hu, Dan Huang, Xiaoli Huang, Hongqing Liang

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1579-1593; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.167

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Article

Immune Infiltration-Related Biomarker ProteinO-Glucosyltransferase 1 to Diagnose Osteoporosis

Yong-bin Zhang, Yu-xuan Fang, Nan Xu, Long-long Tian, Tian-tian Dai, Xing-xing Min, Gui-yu Chen, Nian-xing Liu, Guo-qing Li

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1595-1603; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.168

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Article

Serpin B1 Alleviates Lupus Nephritis via Modulating the Mitogen-Activated Protein Kinase Pathway

Wei Wei, Wei Zou, Wei Han

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1605-1616; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.169

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Article

LncRNA TUSC7 Inhibits the Proliferation and Invasion of Gastric Cancer Cells by Regulating the miR-130b-5p/PCDH9 Axis

Zhiping Yuan, Lixia Zhang, Mingjie He, Huamei Lu

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1617-1626; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.170

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Article

MicroRNA-301a Mediates Doxorubicin Resistance by Up-Regulating the NF-κB in Breast Cancer

Tingyou Zhang, Xiaojuan Wang, Shanshan Deng, Lin Zhou, Xiaowen Sun, Ruizhan Tong, Lin Xu, Ran Li, Xiaorong Yang, Fang Chen, Ning Li

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1627-1636; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.171

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Article

Anti-Inflammatory Effect of Different Solvent Extracts from the Rhizome of Imperata Cylindrica on Lipopolysaccharide-Stimulated RAW264.7 Cells

Chenyuan Luo, Yuming Wei, Shuzhen Li, Chunjun Li, Honglai Zheng

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1637-1646; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.172

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Article

A Model for Predicting the Immune Microenvironment and Prognosis of Patients with Endometrial Cancer Based on Ferroptosis-Associated Genes

Xuewei Xing, Xuan Jin

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1647-1659; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.173

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Article

Development of Rapid Detection Technology for HPV16 Based on CRISPR-Cas12a

Xingzhong Tian, Yuan Xue Yi, Jian Xu, Zeqin Luo, Na Xing, Zhengbing Wang, Sini Chen, Xin Ye, Youliang Shen

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1661-1668; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.174

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Article

The Role of Aspartoacylase Gene Expression on the Onset and Prognosis of Stomach Adenocarcinoma Patients

Yu Zhang, Zunqi Hu, Dejun Yang, Jiapeng Xu, Hongbing Fu, Xin Zhang, Ronglin Yan, Weijun Wang

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1669-1678; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.175

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Article

Long Non-Coding RNA LINC01094 Promotes Metastasis of Gastric Cancer through Activating RhoA/Rho-Associated Coiled-Coil Kinase Pathway

Xin-yu Wang, Zhi-chao Mao, Yong-tang Zhao, Fang Liu, Hua-Min Zhao, Qin Qin, Qiong-yao Zou

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1679-1687; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.176

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Article

Association between Tumor Necrosis Factor-α Receptor Gene Polymorphism and Ankylosing Spondylitis in Han Population

Ling Ge, Jing-Hao Qin, Shao-Bo Yu, Guo-Yong Yin

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1689-1694; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.177

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Article

Berberine Ameliorates Sevoflurane-Induced Neurotoxicity through Activating Nrf2/HO-1 Signaling Pathway

Xiaoping Dong, Xiaonan Liu, Cencen Wang, Zhen Bi

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1695-1704; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.178

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Article

MNX1-AS1 Enhances Cholangiocarcinoma Cell Proliferation and Migration by Increasing HuR-Mediated mRNA Stability of MNX1

Yanneng Xu, Si Xie, Gang Yuan, Wei Hu, Xiangqiong Zhang, Bo Zheng, Jianming Luo, Xun Zhang, Shuhao Xu, Guangyan Si

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1705-1715; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.179

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Article

Identification of a Novel Ferroptosis-Associated Gene Signature of Ulcerative Colitis

Chong Fu, Wenjiao Cai, Yanping Zhang

Journal of Biological Regulators and Homeostatic Agents. 2022, 36(5): 1717-1725; https://doi.org/10.23812/j.biol.regul.homeost.agents.20223605.180

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