Special Issues

Molecular Research in Neurotoxicology
Editor: Mevlut Sait Keles

Submission Deadline: 31 January 2024 (Status: Open)

Special Issue Editor(s)

Prof. Mevlut Sait Keles      Email   |   Website
Department of Medical Biochemistry, Faculty of Medicine, Uskudar University, Istanbul, Turkey
Interests: neurotoxicity; antioxidant activity; boron and its derivates; cancer biochemistry; HPLC analysis; ICP-MS

Special Issue Information

Dear Colleagues,

Neurotoxicity has become a significant health issue today, and it is mainly caused by environmental problems, poor eating habits, personal addictions, and low physical activity.

Neurotoxicity refers to pathologies that develop due to agents that affect the central and peripheral nervous system tissues. In this context, neurons, astrocytes, oligodendrocytes, and microglial cells are damaged in the brain. The most common factors affecting neurons are hypoxia and external or internal chemical injurious agents. Neurons are the most energy-consuming cells in the body. In hypoxia, cellular energy metabolism is affected, leading to a decrease in energy production. Supporting glial cells try to reduce the energy deficit in neurons through monocarboxylate transporters. Apart from the decrease in the blood flow to the brain, many chemical toxic agents are essential in neurotoxicity by crossing the blood-brain and blood-CSF barrier.

Overeating or excessive carbohydrate consumption also causes damage to neurons. Peripheral neuropathy is the most common chronic complication of diabetes. Also, general nutritional defects caused by vitamin, mineral, and protein deficiencies occurring due to poor eating habits lead to neurotoxicity.

In addition, personal addiction to alcohol, cigarettes, some addictive agents and some drugs also creates neurotoxic effects. Alcohol disrupts energy metabolism and vitamin use, cigarettes cause cellular damage due to the carcinogenic and toxic substances, and addictive agents and drugs disrupt neurotransmitter activity.

Therefore, exposure to substances that cause neurotoxicity is inevitable today. Studies on this subject will undoubtedly make significant contributions to neurological well-being. In this context, this special issue of neurotoxicity will make an important contribution to this field.

Prof. Mevlut Sait Keles
Guest Editor


hypoxia; multiple sclerosis; neural damage; neurodegenerative diseases; biochemistry of Alzheimer Disease

Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://www.biolifesas.org/journalx_brha/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.

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