Submission Deadline: 31 December 2023 (Status: Open)
Special Issue Editor(s)
Marcello Iriti Email
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy
Interests: bioactive phytochemicals; essential oils; nutraceuticals; phytotherapeutics; functional foods; mediterranean diet; ethnopharmacology; antimicrobials; antimicrobial resistance; one health; cancer chemoprevention; anticancer agents; antineoplastic resistance; cardioprotection; neuroprotection; bioavailability; pharmacokinetics
Special Issue Information
Preclinical (in vitro and in vivo) studies have highlighted the plethora of biological activities of bioactive phytochemicals, such as antimicrobial, antioxidant/pro-oxidant, anti-inflammatory, and cytotoxic and immunomodulating activities. Plant extracts and essential oils generally possess a multi-target mechanism of action, making them promising antimicrobial, cardioprotective, neuroprotective, anti-cancer, anti-diabetic, anti-obesity, and anti-aging agents. It is possible that phytochemicals can also be used as adjuvant and sensitizing agents for use in combination with conventional [antimicrobial and anticancer] therapies to increase their efficacy, reduce their adverse effects, decrease the risk of selecting resistant microbial strains or cancer cells, and even reverse resistance, including radioresistance. However, despite positive data from cell cultures and animal models for this type of application, the evidence in humans remains incomplete. The efficacy of plant natural products in the prevention and treatment of communicable and non-communicable diseases should be further substantiated on the basis of evidence-based phytotherapy. Indeed, more clinical trials of plant natural products in healthy subjects and subjects with specific diseases are needed to improve the knowledge about their effective dose, route of administration, bioavailability, adverse effects and drug interactions.
phytotherapeutics; nutraceuticals; ethnopharmacology; antimicrobial resistance; one health; cancer chemoprevention; anticancer agents; antineoplastic resistance; cardioprotection; neuroprotection; bioavailability; pharmacokinetics
Manuscript Submission Information
Manuscripts should be submitted via our online editorial system at https://www.biolifesas.org/journalx_brha/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.
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