Submission Deadline: 15 November 2023 (Status: Open)
Special Issue Editor
Dr. Dongwon Lee
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Website
Department of BIN Convergence Technology and Polymer Nano Science and Technology, Chonbuk National University, Jeonju, Republic of Korea
Interests:
bioengineering; basic research; protein modifications; molecular mechanisms; ncRNA; clinical translational medicine; immune cell; cytokines
Special Issue Information
Dear Colleagues,
Physical properties of cells and extracellular microenvironment are indispensable for maintaining homeostasis. Cells have evolved sophisticated systems to perceive both, their nature and artificial microenvironments. These stimuli is transformed into biochemical signals that control multiple aspects of cell behaviors, with the consequent modulation of different human diseases, including inflammation and malignant tumors. For that reason, a thorough study of the mechano-transduction system and promising targets need immediate research to provide an experimental basis for the development of safe and effective alternative or combination therapeutic drugs.
Not only do intracellular signals, gene expression, DNA/RNA/protein modification, cell phenotype and function respond to mechanical changes, but also the mechanical properties of the cells change. Using multi-disciplinary biotechnology to study the biological mechanism of human disease to clarify its basic mechanism and clinical perspective will help to develop new methods for the treatment and intervention of different diseases.
The aim of this research topic is to publish a comprehensive list of articles under the topic title “New Insights into Mechanobiology of Inflammation and Tumors: Molecular Basis and Clinical Perspectives”. The collection will cover multiple aspects, such as basic translational and clinical research related to molecular biology, and biochemistry aspects.
Submissions in any of the following categories will be considered: Original Research articles, Reviews and Mini-Reviews. Manuscripts should be related to the next topics:
- Novel mechanotransduction mechanisms and newly developed therapeutic strategies for treating the dysregulated mechanosensing pathways.
- Development of in vitro and in vivo models to produce novel insights about human diseases.
- Advancement in molecular engineering, including live cell imaging and bio-nanotechnology to visualize and elucidate the molecular mechanisms by which cells perceive and respond to mechanical microenvironmental cues.
- Quantitative characterization of the physical properties of cells at molecular and cellular levels and its implications in physiology and pathophysiology in health and disease.
Dongwon Lee
Guest Editor
Keywords
cell biology; pathology; cytology; oncology; clinical oncology; inflammation; gene expression; bioengineering and translational medicine
Manuscript Submission Information
Manuscripts should be submitted via our online editorial system at https://www.biolifesas.org/journalx_brha/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.
