J Biol Regul Homeost Agents. 2021 Jan-Feb;35(1 Suppl. 2):45-50. doi: 10.23812/21-1supp2-9.

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The management of chronic rhinosinusitis in clinical practice: An International Survey

Passali D1, Passali GC2,3, Piemonte M4, Cingi C5, Ciprandi G6; *International Study Group on Chronic Rhinosinusitis: Agius A, Ahluwalia H, Al Abri A, Alho OP, Bachert C, Balaji N, Balsevicius T, Baudoin T, Benghalem A, Bhattarai H, Boci B, Bunnang C, Carvajal JD, Charalambous M, Chen L, Cuilty Siller C, Dimov P, Din MF, Douglas RG, Durham SR, Eloy P, Erdenechuluun B, Felippu Neto A, Fliss DM, Gendeh S, Gerlinger I, Golusinski W, Hadi U, Hasbellaoui M, Heinichen J, Huizing EH, Jenko K, Kamel R, Kawauchi H, Kennedy D, Kern E, Kiesling Calderon V, Kopacheva Barsova G, Landis BN, Lopatin A, Lubbe D, Marakyna-Kibak L, Matuba KMD, Melendez A, Mesbahi A, Metsmaa M, Mladina R, Mosges R, Nassir TH, Negm HMA, Nguyen Thi ND, Nyembue DT, Onerci TM, Pais Clemente M, Papavassiliou AG, Patil NP, Perdomo Flores EA, Plzak J, Rahman HA, Rhee CS, Rodriguez HA, Sacks R, Salaverry F, Sandul A, Sarafoleanu CC, Sarandeses Garcia A, Shukuryan AK, Sicak M, Siguror K, Silva Chacon F, Stankovic M, Stierna LEP, Stott C, Tariq Rafi SM, Talishinskiy A, Tarafder KH, Tong M, Tulebayev RK, Vicente GM, Von Buchwald C, Wagener M, Wang DY, Wardani RS, Yeh TH, Zabolotnyi D.

Author information

1 International Federation ORL Societies (IFOS) Executive Board members Rome Italy.
2 UOC di Otorinolaringoiatria, Dipartimento Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della testa collo. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
3 Institute of Otolaryngology, Università Cattolica del Sacro Cuore, Policlinico Agostino Gemelli, Rome, Italy.
4 ENT Clinic, Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy.
5 Department of Otorhinolaryngology, Eskisehir Osmangazi University, Eskisehir, Turkey.
6 Consultant allergist, Casa di Cura Villa Montallegro, Genoa, Italy.


Chronic rhinosinusitis (CRS) is a common disease and is currently classified in two main phenotypes: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). A panel of international experts conducted the present survey. A questionnaire, containing 25 questions, was completed by each member of the panel. About half of patients with suspected CRS had confirmed diagnosis. CRSwNP affected 31% of CRS patients. Endoscopy and CT were ever performed. Rhinitis and asthma were frequent comorbidities. Intranasal corticosteroids were prescribed on average in 86% of patients. Nonadrenergic compounds were prescribed by 71% of experts. Surgery for CRSwNP was performed in about half of patients; repeated intervention occurred in about one/third. In conclusion, the current survey demonstrated that CRS requires thorough diagnostic work-up, and the most common therapeutic approach is mainly based on intranasal corticosteroids, non-adrenergic decongestants, and surgery.


Survey, chronic rhinosinusitis; intranasal corticosteroids, nasal polyps, non-adrenergic decongestants, surgery

Publication type

  • Observational Study

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