J Biol Regul Homeost Agents. 2021 Jan-Feb;35(1 Suppl. 2):27-32. doi: 10.23812/21-1supp2-6.

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Sleep-disordered breathing in the otorhinolaryngological practice

Ameli F1, Mignosi S1, Brocchetti F1, Gallo F2, Passali FM3, Damiani V4, Asmanov A5, Ciprandi G6.

Author information

1 Otorhinolaryngology Unit, Casa di Cura Villa Montallegro, Genoa, Italy.
2 Health Sciences Department, Genoa University, Genoa, Italy.
3 ENT Department, University Tor Vergata, Rome, Italy.
4 Medical Department, DMG Italy, Pomezia, Italy.
5 Pirogov Russian National Research Medical University, Moskow, Russia.
6 Consultant allergist, Casa di Cura Villa Montallegro, Genoa, Italy.


Sleep-disordered breathing (SDB) is a common disorder in childhood. Snoring and obstructive sleep apnea represents a demanding challenge for both paediatricians and otolaryngologists. This real-life study investigated the association of demographic and clinical factors on snoring and sleep apnea in children consecutively visited. In this study, 1,002 children (550 males, mean age 5.77 + 1.84 years), complaining upper airway symptoms, were prospectively enrolled during 2015-2017. Medical history, clinical examination, and fiberoptic nasopharyngoscopy were performed in all children. Tonsil hypertrophy significantly predicted sleep apnea (OR 95.08) and snoring (OR 5.44). Asthma comorbidity significantly predicted snoring (OR 2.26). Breastfeeding could be a protective factor for sleep apnea (OR =0.37). SDB is a frequent disorder observable in otorhinolaryngological practice. Tonsil hypertrophy and asthma could be considered predicting factors for both snoring and sleep apnea, whereas breastfeeding was a protective factor for SDB.


asthma, breastfeeding, children, sleep apnea, sleep-disordered-breathing; snoring, tonsil

Publication type

  • Observational Study

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