J Biol Regul Homeost Agents. 2021 Jan-Feb;35(1 Suppl. 2):55-59. doi: 10.23812/21-1supp2-11.

>>> Request Full Article

Laryngopharyngeal reflux management in clinical practice

Ciprandi G1, Passali D2, Damiani V3, Mezzedimi C4, Bellussi LM2, Passali GC5,6; *Laryngopharyngeal Reflux Study Group: R. Albera , M. De Vincentiis, C.A. Leone, N. Lombardo, A. Marzetti, G. Motta, G. Panetti, M. Piemonte, P. Ruscito, F. Scasso.

Author information

1 Consultant allergist, Casa di Cura Villa Montallegro, Genoa, Italy.
2 International Federation ORL Societies (IFOS) Executive Board members Rome Italy.
3 Medical Department, DMG Italy, Pomezia, Italy.
4 ENT Clinic University School Siena Italy.
5 UOC di Otorinolaringoiatria, Dipartimento Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della testa collo. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
6 Institute of Otolaryngology, Università Cattolica del Sacro Cuore, Policlinico Agostino Gemelli, Rome, Italy.


Laryngopharyngeal reflux (LPR) is an inflammatory reaction of the mucosa of the pharynx, larynx, and other associated upper respiratory organs, caused by a reflux of stomach contents outside the esophagus. LPR is considered a relatively new clinical entity with a vast number of clinical manifestations that are sometimes treated empirically and without a correct diagnosis. Alginate is a reasonable therapeutic option as a first-line or add-on option. A survey included 35 Italian otorhinolaryngologists. The survey considered ten practical queries. LPR is a common disease in clinical practice. History and fiber-optic endoscopy constitute the main diagnostic tools. Alginates represent a frequent medication to treat LPR both as first-line and add-on. The mean effectiveness rate is 44% for first-line choice and 76% for the add-on. In conclusion, the current survey provided exciting information about the management of LPR in clinical practice.


alginate, laryngopharyngeal reflux, management, otorhinolaryngologist, survey

Publication type

  • Observational Study

>>> Request Full Article

You may also like...