J Biol Regul Homeost Agents. 2020 Nov-Dec;34(6):2345-2352. doi: 10.23812/20-411-L.

Efficacy of a nasal spray containing N-acetylcysteine in hypertonic solution in the treatment of nonallergic chronic rhinitis with goblet cell metaplasia

Maffezzoni E1, Notargiacomo M2, Agostini S3, Gelardi M4.

Author information

1  Rhinocytoallergology Unit, Istituto Figlie di San Camillo, Cremona, Italy.
2  Otorhinolaryngology Unit, Melzo Hospital, Milan, Italy.
3  Scientific Direction, Pharma Line, Milan, Italy.
4  Unit of Otolaryngology, University of Foggia, Foggia, Italy.


N-acetylcysteine, chronic rhinitis, goblet cell metaplasia, hypertonic saline solution, nasal cytology, topical therapy

Publication type

  • Letter

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