JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS Vol. 33, no. 3, 949-956 (2019)


Characterization of microRNA in the follicular fluid of patients undergoing assisted reproductive technology.

Mencaglia L1, Cerboneschi M2,3, Ciociola F1, Ricci S1, Mancioppi I1, Ambrosino V1, Ferrandi C4, Strozzi F4, Piffanelli P4, Grasselli A5.

Author information

1 Azienda USL Sud Est, Regione Toscana Centro di PMA Ospedale Santa Margherita La Fratta Cortona, Arezzo, Italy.
2 NEXT Genomics Srl, Prato, Italy.
3 Department of AgriFood Production and Envi¬ronmental Sciences (DISPAA), University of Florence, Sesto Fiorentino (Florence), Italy.
4 PTP Science Park, Lodi, Italy.
5 IBSA Farmaceutici Italia Srl, Medical Scientific Division, Lodi, Italy.

Abstract

Female fertility plays a decisive role in the reproduction of mammals, with related issues that include oocyte or embryo quality, establishment of pregnancy, and the physiology of the tissues that contribute to reproduction and metabolic disorders associated with reproductive failure. Although reproductive failure may be attributed to various factors in different species, female infertility is largely controlled by a number of molecular signals that can be regulated in a cycle- and tissue-dependent manner.

KEYWORDS:

assisted reproductive technology, follicular fluid, micro RNA, pregnancy outcome

Publication type

  • Letter

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