Special Issues

Oxidative Stress during Aging and the Remediation by Exercises & Nutrition
Editor: Rafael Herling Lambertucci and Marcelo Paes de Barros

Submission Deadline: 31 December 2023 (Status: Open)

Special Issue Editor

Prof. Rafael Herling Lambertucci      Email   |   Website
Department of Biosciences, Federal University of São Paulo (UNIFESP), Santos, Brazil
Interests: antioxidant; oxidative stress; exercise; skeletal muscle; metabolism; cardiac tissue

Prof. Marcelo Paes de Barros      Email   |   Website
Institute of Physical Activity and Sports Science (ICAFE), Cruzeiro do Sul University, São Paulo, Brazil
Interests: antioxidant; free radicals; oxidative stress; aging; exercise

Special Issue Information

Dear Colleagues,

The free radical theory of aging supports that the continuous accumulation of unrepaired oxidative damage of macromolecules throughout the lifespan is the molecular basis of age-related physiological dysfunction. Oxidative accumulation rate dictates cellular/tissue senescence and, chronically, age-related physical and mental limitations, including its comorbidities. The positive effects of regular exercises rely on the hormesis principle: regular physiological challenges imposed by moderate exercises will demand gradually antioxidants progressive responses, housekeeping proteins and cytoprotective enzymes, which, altogether, improve the health conditions of those active subjects. Most of these positive adaptations occur via redox signaling pathways. Moreover, adequate nutrition, rich of antioxidants and micronutrient provisions, will assure proper redox balances that sustain sufficient redox signals for positive adaptations, without leading to exacerbated oxidative stress in active subjects. This SI will focus on the protective effects of regular exercises and/or nutrition (including supplementation) against age-related progressive oxidative stress conditions and its comorbidities. Original articles and reviews are welcome in the topic of gerontology, exercise and nutrition field.

Prof. Rafael Herling Lambertucci and Prof. Marcelo Paes de Barros
Guest Editors


free radicals; elderly; supplementation; sarcopenia; exercise

Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://www.biolifesas.org/journalx_brha/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.

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