Dear Colleagues,

Cardiovascular diseases (CVDs) are a cluster of disease affecting most of the population worldwide. Approximately 182 million cases of CVDs are reported worldwide every year. CVDs are also responsible for the development of other co-morbidities which further diminish patients' quality of life. CVDs have complex pathogenesis, and many factors are corelated with CVDs. Due to the complex pathogenesis, pharmacotherapy of CVDs is a challenge for medical fraternity. Moreover, comprehensive cure is not achieved in several cardiovascular diseases. Plethora of allopathic drugs are available for the treatment/management of CVDs but is associated with side effects and the cost of the therapy also limits the achievement of therapeutic goals.

Long term use of these allopathic drugs might result in some severe hidden side-effects which might turn out to be life-threatening later in life. Given these allopathic medicines related problems, scientists have focused research on an alternative therapy called Ayurveda or natural products that can be used to manage CVDs. According to scientific literature, a number of natural products are found to possess significant efficacy in the treatment of cardiovascular diseases at pre-clinical level. Still, these herbal drugs of natural products are not used as a first line therapeutic agent for the treatments of CVDs. Lack of specific mechanism of action and purity of herbal drugs are the major limitations for not considering herbal drugs as first line drugs. Considering this viewpoint, this special issue is focused on the utilisation of herbal drugs from pre-clinical system to clinical setups. This issue will comprise articles related to utilisation of herbal products for the treatment of CVDs, mechanism of action of herbal drugs in CVDs, clinical trials on herbal drug and regulatory guidelines for the use of herbal drugs for the treatment pf CVD and recent updates on the use of herbal drugs in clinical practice.

Randhir Singh Dahiya
Guest Editor

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